Engine Ventures backs founders solving the world’s biggest problems through the convergence of breakthrough science, engineering, and leadership. These companies are pioneering science and technology that will change the future for the better.
Generating diverse genomes to scale and digitalize biomanufacturing.
Decoding the brain’s biology to cure neurological diseases.
A secure, resilient operating system, designed for the cloud computing era.
Cheaper, sustainable electrolyzer solution enables hydrogen delivery to the world.
A materials breakthrough to eliminate the climate impact of cooling.
Transforming cancer therapy by targeting the extracellular matrix.
Applying a fundamental mathematical insight to the problem of turbulence.
Harnessing a novel bio-analyte to transform patient care.
Transforming industrial catalysts with computational design.
Reinventing carbon capture with novel materials.
Tackling the world’s hardest computational challenges with scalable quantum computers.
Next generation of super metal alloys, enabling a critical step to the energy transition.
Enabling precision-genomic editing with single-stranded DNA technology.a
Repurposing wastewater into low-cost feedstock to enable biomanufacturing at scale.
Biomanufacturing of tree and plant products for supply surety and to prevent deforestation.
Using wireless charging to unlock new opportunities in mobility and medicine.
Decarbonizing gas separations to eliminate one gigaton of carbon emissions per year.
Building implantable electronics as soft as the brain to amplify brain-machine communication.
Cost-effective, zero-carbon cement produced via electrochemistry.
Decarbonizing chemicals synthesis using a low-cost distributed platform.
Reinventing the architecture of electricity transmission to enable a fully decarbonized grid.
Powering the future of public transit.
Optical interconnect for semiconductors. A Photonic Fabric for chip-to-chip and on-chip data movement.
Creating beautiful, intelligent, and scalable building systems that raise the standards of low-to-high rise construction.
Universal access to geothermal energy through disruptive millimeter wave drilling technology.
Data analysis that will transform wastewater infrastructure into public health observatories.
Enabling the next era of fully electrified heavy machinery.
The fastest, most sustainable, and most efficient lithium extraction platform.
The future of sustainable skincare.
Optimizing the resources at the heart of every cloud computation.
Chemical manufacturing driven by light, enabling cheaper scalable on-site production.
Breakthrough mitochondrial-based therapies for neurological diseases.
Unlocking the immune system to fight cancer and disease.
Efficient, lower-cost production of steel and alloys with zero emissions.
Making our food system more resilient.
Ultra-efficient optical circuits to de-bottleneck data centers and telecom networks.
Industrial Generative AI for Industrial-Scale Problems.
Creating safe, unlimited, carbon-free fusion power for the grid in 10-15 years.
Significantly more efficient electronics: from cell towers to data centers.
Curing the world’s toughest diseases by automating personalized medicine.
Cellular engineering, at unparalleled speeds, from discovery to the clinic.
Automating the logistics industry with a humanistic AI-powered autonomous driving system.
Cost-effective, multi-day energy storage systems that will enable a reliable and fully-renewable electric grid.
Decarbonizing separation of liquids — the core of many industrial processes.
Using fluorescence to unlock new layers of information.
Ultrasound drug delivery for difficult-to-treat diseases.