The Engine backs founders solving the world’s biggest problems through the convergence of breakthrough science, engineering, and leadership. These companies are pioneering science and technology that will change the future for the better.
A materials breakthrough to eliminate the climate impact of cooling.
Targeting the extracellular matrix for a new therapeutic platform.
Applying a fundamental mathematical insight to the problem of turbulence.
Harnessing a novel bio-analyte to transform patient care.
Transforming industrial catalysts with computational design.
Reinventing carbon capture with novel materials.
Building next-generation quantum computers
Enabling materials for the next generation of industrial innovation.
Harnessing single-stranded DNA for precision genome editing.
Valorizing wastewater to fuel biomanufacturing.
Growing plant material in the laboratory as an alternative to deforestation.
Using wireless charging to unlock new opportunities in mobility and medicine.
Decarbonizing gas separations to eliminate one gigaton of carbon emissions per year.
Building implantable electronics as soft as the brain to amplify brain-machine communication.
Producing cost-effective, zero-carbon cement using renewable electricity.
Converting wasted resources into valuable liquid chemicals through a low-cost, distributed platform.
Reinventing the architecture of electricity transmission to enable a fully decarbonized grid.
Powering the future of public transit.
Harnessing photonics to lead the next wave of advancements in AI computation.
Creating beautiful, intelligent, and scalable building systems that raise the standards of low-to-high rise construction.
Universal access to geothermal energy through disruptive millimeter wave drilling technology.
Data analysis that will transform wastewater infrastructure into public health observatories.
Enabling the next era of fully electrified heavy machinery.
The fastest, most sustainable, and most efficient lithium extraction platform.
The future of sustainable skincare.
Optimizing the resources at the heart of every cloud computation.
Chemical manufacturing driven by light, enabling cheaper scalable on-site production.
Breakthrough mitochondrial-based therapies for neurological diseases.
Unlocking the immune system to fight cancer and disease.
Efficient, lower-cost production of steel and alloys with zero emissions.
A natural coating that reduces food spoilage and packaging waste.
Ultra-efficient optical circuits to de-bottleneck data centers and telecom networks.
Industrial Generative AI for Industrial-Scale Problems.
Creating safe, unlimited, carbon-free fusion power for the grid in 10-15 years.
Significantly more efficient electronics: from cell towers to data centers.
A tissue foundry for regenerative medicine.
Cellular engineering, at unparalleled speeds, from discovery to the clinic.
Automating the logistics industry with a humanistic AI-powered autonomous driving system.
A real-time satellite network connecting space to Earth 24/7.
Making renewable energy available 24/7 with bidirectional power plants.
Up to 90% energy savings in separation processes in the pulp & paper, chemical, and dairy industries.
Using fluorescence to unlock new layers of information.
Ultrasound drug delivery for difficult-to-treat diseases.